General Information

  • ID:  hor000463
  • Uniprot ID:  E9GSK4
  • Protein name:  Allatostatin B4
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  RWDQLHGAW
  • Length:  9(153-161)
  • Propeptide:  MQFWQCPLLLMVSLIAAINTQQTPSQRLEPNQVAGLVELHQQLEQPREHQQQQQHHQQQPEQPAQADNKDYAPSPAVLLQLTPSDWKNTQDKRNNWNRMQGMWGKRSQQQSDESALSEMTPPRMVKRAWSDLSQQGWGKRSWTQLHGVWGKRRWDQLHGAWGKRTPDQLEDDSKAEQPENSQEDEDQQSSSEVEREEANDSDDTVENSKRSGWNKMQGVWGKRSSSSSKTNSGPAIEGMGNNDLLLLISGTGDQL
  • Signal peptide:  MQFWQCPLLLMVSLIAAINT
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9GSK4-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000463_AF2.pdbhor000463_ESM.pdb

Physical Information

Mass: 131117 Formula: C54H73N17O13
Absent amino acids: CEFIKMNPSTVY Common amino acids: W
pI: 7.55 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 4
Hydrophobicity: -125.56 Boman Index: -2151
Half-Life: 1 hour Half-Life Yeast: 2 min
Half-Life E.Coli: 2 min Aliphatic Index 54.44
Instability Index: 5157.78 Extinction Coefficient cystines: 11000
Absorbance 280nm: 1375

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones